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Wednesday, October 26, 2005

BULLOUS PEMPHIGOID


Bullous Pemphigoid(B.P.) ===>
In B.P.,blister are subepidemal with excess eosinophils.
AutoAg.=Bullous pemphigoid Ag(BPA G1 & BPA G2)
Seen in Elderly >60yrs.
Lesion site=Flexor surfaces of limbs
lower abdomen
Oral mucosa(10-40%)
Direct ImmunoFluroscence microscopy shows Linear Deposits of IgG &/or C3 in epidermal basement memb.zone.
T.O.C./D.O.C=Systemic Glucocorticoids

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