PGMEEnotes: Transplant Rejections
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Thursday, November 17, 2005

Transplant Rejections

PointsRejection Mech.Timing
1Hyper-acute rejectionRecipients has preformed high titre antibody. Immediate reaction of Ab. and complement. Min. to Hrs.
2Accelerated rejection Reactivation of sensitized T-cell.Days
3Acute rejectionPrimary activation of T-cells.Days to weeks
4Chronic rejectionAb., Immune complexes, slow cellular reaction, recurrence of disease…. cause unknown.Mths. to Years

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