Transplant Rejections

Points	Rejection	Mech.	Timing
1	Hyper-acute rejection	Recipients has preformed high titre antibody. Immediate reaction of Ab. and complement.	Min. to Hrs.
2	Accelerated rejection	Reactivation of sensitized T-cell.	Days
3	Acute rejection	Primary activation of T-cells.	Days to weeks
4	Chronic rejection	Ab., Immune complexes, slow cellular reaction, recurrence of disease…. cause unknown.	Mths. to Years

EXTRAOCULAR MUSCLES